Publications

Publications by the Klein Lab

^ High school student
# Undergraduate student
$ Graduate student
% Postdoc
* Equal contributors

2024
  • Uchendu, C.G.$,  Guan, Z., and Klein, E.A. Spatial organization of bacterial sphingolipid synthesis enzymes. J. Biological Chemistry (2024), 300(5): 107276. https://doi.org/10.1016/j.jbc.2024.107276
  • Shain, D.H. and Klein, E.A. Genome assembly of Pseudomonas sp. strain SED1T, a psychrotolerant bacterium isolated from Deception Glacier (Washington, USA). Microbiol Resour Announc (2024), 0:e00125-24. https://doi.org/10.1128/mra.00125-24
2023
  • Dhakephalkar T.$, Stukey, G.J.$, Guan, Z., Carman, G.M., Klein, E.A. Characterization of an evolutionarily distinct bacterial ceramide kinase from Caulobacter crescentus. J. Biological Chemistry (2023), 299(7): 104894. https://doi.org/10.1016/j.jbc.2023.104894
2022
  • Zik, J.J., Yoon, S.S., Guan, Z., Skidmore, G.S.$, Gudoor, R.R., Davies, K.M., Deutschbauer, A.M., Goodlett, R., Klein, E.A., Ryan, K.R. Caulobacter requires anionic sphingolipids and deactivation of fur to lose lipid A. Cell Reports (2022), 39(9): 110888. https://doi.org/10.1016/j.celrep.2022.110888
  • Stankeviciute, G.S.$, Tang, P., Ashley, B., Chamberlain, J.D.$, Hansen, M.E.B., Coleman, A.^, D’Emilia, R.#, Fu, L.^, Mohan, E.C., Nguyen, H.^, Guan, Z., Campopiano, D.C., Klein, E.A. Convergent evolution of bacterial ceramide synthesis. Nature Chemical Biology (2022), 18(3): 305-312. https://doi.org/10.1038/s41589-021-00948-7
2020
  • Werner, J.N.*, Handuo S.*, Hsin, J., Huang, K.C., Gitai, Z., Klein, E.A. AimB is a small protein regulator of cell size and MreB assembly. Biophysical Journal (2020), 119(3): 593. https://doi.org/10.1016/j.bpj.2020.04.029.
  • Revaitis, N.T.$, Niepielko, M.G., Marmion, R.A., Klein, E.A., Piccoli, B., Yakoby, N. Quantitative analyses of EGFR localization and trafficking dynamics in the follicular epithelium. Development (2020), 147(15): dev183210. https://doi.org/10.1242/dev.183210
  • Moorthy, S.%, Byfield, F.J., Janmey, P.A., Klein, E.A. Matrix stiffness regulates endosomal escape of uropathogenic E. coli. Cellular Microbiology (2020), 22(5): e13196. https://doi.org/10.1111/cmi.13196.
  • de Young K.D.$, Stankeviciute G.$ and Klein, E.A. Sugar-phosphate metabolism regulates stationary-phase entry and stalk elongation in Caulobacter crescentus. J. Bacteriology. (2020), 202(4): e00468. https://doi.org/10.1128/JB.00468-19.
2019
  • Stankeviciute G.$ and Klein, E.A. Purification and HPLC Analysis of Cell Wall Muropeptides from Caulobacter crescentus. Bio-protocol. (2019), 9(21): e3421. https://doi.org/10.21769/BioProtoc.3421.
  • Klein, E.A. Bacterial sphingolipids: Perhaps not as rare as we thought? ASBMB Today (2019). http://www.asbmb.org/asbmbtoday/201910/News/Lipidnews/
  • Moffett S.X., Klein, E.A., Brannigan, G., Martin, J.V. L-3,3’,5-triiodothyronine and pregnenolone sulfate inhibit Torpedo nicotinic acetylcholine receptors. PLoS One. (2019), 14(10): e0223272. https://doi.org/10.1371/journal.pone.0223272
  • Mandal, K., Pogoda, K., Nandi, S., Mathieu, S., Kasri, A., Klein, E.A., Radvanyi, F., Goud, B., Janmey, P.A., Manneville, J.B. Role of a kinesin motor in cancer cell mechanics. Nano Letters (2019), 19(11): 7691. https://doi.org/10.1021/acs.nanolett.9b02592
  • Stankeviciute G.$, Guan, Z., Goldfine, H., Klein, E.A. Caulobacter crescentus adapts to phosphate starvation by synthesizing anionic glycoglycerolipids and a novel glycosphingolipid. mBio. (2019), e00107-19. https://doi.org/10.1128/mBio.00107-19.
  • Stankeviciute G.$, Miguel, A.V., Radkov, A., Chou, S., Huang, K.C., Klein, E.A. Differential modes of crosslinking establish spatially distinct regions of peptidoglycan in Caulobacter crescentus. Mol. Micro. (2019), 111(4): 995-1008. https://doi.org/10.1111/mmi.14199.
2017
  • Ratti, M.#, Naddeo, J.J.#, Griepenburg, O’Malley, S.M., Bubb, D.M., Klein, E.A. Production of Metal Nanoparticles by Pulsed Laser-ablation in Liquids: A Tool for Studying the Antibacterial Properties of Nanoparticles. J. Vis. Exp. (2017), 124: e55416. https://doi.org/10.3791/55416.

2016
  • Ratti, M.#*, Naddeo, J.J.#*, Tan, Y.#, Griepenburg, J.C., Tomko, J.#, Trout, T.#, O’Malley, S.M., Bubb, D.M., Klein, E.A. Irradiation with visible light enhances the antibacterial toxicity of silver nanoparticles produced by laser ablation. Applied Physics A (2016), 122(4):346. https://doi.org/10.1007/s00339-016-9935-8.
  • Moorthy,S., Keklak, J.$, Klein, E.A. Perspective: adhesion mediated signal transduction in bacterial pathogens. Pathogens (2016), 5(1):23. https://doi.org/10.3390/pathogens5010023.
2015
  • Naddeo, J.J.#*, Ratti, M.#*, O’Malley, S.M., Griepenburg, J.C., Bubb, D.M., Klein, E.A. Antibacterial properties of nanoparticles: a comparative review of chemically synthesized and laser-generated particles. Advanced Science, Engineering, and Medicine (2015), 7(12):1044-1057. https://doi.org/10.1166/asem.2015.1811.
Publications prior to Rutgers
  • Klein, E.A. and Gitai, Z. Draft genome sequence of uropathogenic Escherichia coli strain J96. Genome Announc. (2013),1(1):e00245-12.
  • Klein, E.A.*, Schlimpert, S.*, Hughes, V., Brun, Y.V., Thanbichler, M., and Gitai, Z. Physiological role of stalk lengthening in Caulobacter crescentus. Commun Integr Biol (2013), 6:e24561.
  • Schlimpert, S.*, Klein, E.A.*, Briegel, A., Hughes, V., Kahnt, J., Bolte, K., Maier, U.G., Brun, Y., Jensen, G.J., Gitai, Z., and Thanbichler, M. General Protein Diffusion Barriers Create Compartments within Bacterial Cells. Cell (2012), 151(6):1270-82.
  • Levental, I., Levental, K.R., Klein, E.A., Assoian, R.K., Miller, R.T., Wells, R.G., and Janmey, P.A. A simple indentation device for measuring micrometer-scale tissue stiffness. Physics: Condensed Matter (2010), 22(19): 194120.
  • Cerezo, A., Guadamillas, M.C., Goetz, J.G., Sanchez-Perales, S., Klein, E.A., Assoian, R.K., and del Pozo, M.A. Absence of caveolin-1 increases proliferation and anchorage independent growth by a Rac-dependent, Erk-independent mechanism. Molecular and Cellular Biology (2009), 29(18):5046-59.
  • Klein, E.A., Castagnino P., Yin, L., Byfield, F.J., Kothapalli, D., Xu, T., Levental, I., Hawthorne, E., Janmey, P.A., and Assoian, R.K. Cell cycle control by physiological matrix elasticity and in vivo tissue stiffening. Current Biology (2009), 19(18):1511-8.
  • Assoian, R.K. and Klein E.A. Growth control by intracellular tension and extracellular stiffness. Trends Cell Biol (2008), 18(7):347-52.
  • Klein, E.A. and Assoian, R.K. Transcriptional regulation of the cyclin D1 gene at a glance. J Cell Sci. (2008), 121(23):3853-7.
  • Yang, C., Klein, E.A., Assoian, R.K., Kazanietz, M.G. Heregulin beta1 Promotes Breast Cancer Cell Proliferation through Rac/Erk-dependent Induction of Cyclin D1 and p21 Cip1. Biochem J (2008), 410(1):167-75.
  • Klein, E.A., Campbell, L.E., Kothapalli, D., Fournier, A.K., Assoian, R.K. Joint requirement for Rac and ERK activities underlies the mid-G1 phase induction of cyclin D1 and S phase entry in both epithelial and mesenchymal cells. J Biol Chem (2008), 83(45):30911-8.
  • Klein, E.A., Yung, Y., Castagnino, P., Kothapalli, D., Assoian, R.K. Cell adhesion, cellular tension, and cell cycle control. Methods Enzymol (2007), 426:155-75.
  • Klein, E.A., Yang, C., Kazanietz, M.G., Assoian, R.K. NFkappaB-independent signaling to the cyclin D1 gene by Rac. Cell Cycle (2007), 6(9):1115-21.